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A Blueprint for Real-Time Functional Mapping via Human Intracranial Recordings.
The surgical treatment of patients with intractable epilepsy is preceded by a pre-surgical evaluation period during which intracranial EEG recordings are performed to identify the epileptogenic network and provide a functional map of eloquent cerebral areas that need to be spared to minimize the risk of post-operative deficits. A growing body of research based on such invasive recordings indicates that cortical oscillations at various frequencies, especially in the gamma range (40 to 150 Hz), can provide efficient markers of task-related neural network activity. PRINCIPAL FINDINGS: Here we introduce a novel real-time investigation framework for mapping human brain functions based on online visualization of the spectral power of the ongoing intracranial activity. The results obtained with the first two implanted epilepsy patients who used the proposed online system illustrate its feasibility and utility both for clinical applications, as a complementary tool to electrical stimulation for presurgical mapping purposes, and for basic research, as an exploratory tool used to detect correlations between behavior and oscillatory power modulations. Furthermore, our findings suggest a putative role for high gamma oscillations in higher-order auditory processing involved in speech and music perception. CONCLUSION/SIGNIFICANCE: The proposed real-time setup is a promising tool for presurgical mapping, the investigation of functional brain dynamics, and possibly for neurofeedback training and brain computer interfaces.
PLoS ONE. 2007 Oct 31;2(10):e1094. Lachaux JP, Jerbi K, Bertrand O, Minotti L, Hoffmann D, Schoendorff B, Kahane P. INSERM, U821, Lyon, F-69500, France.
One of the most natural human instincts is to seek an ideal mate. There are many factors that come into consideration. Many of them involve instinctual biological urges and an innate desire to find someone who meets very distinct criteria regarding height, shape, and symmetry – factors that we often call beauty. Generally, a man is looking for a woman who is able to bear children. And, a woman is normally more attracted to someone who can provide safety and security. Often this means that a woman is seeking a man who displays physical prowess. However, I’ve noticed how intellect and financial...
The miracles of modern medicine are not be taken lightly. The mere fact that the longevity of the average person is much longer than it was a few decades ago should be sufficient evidence of its value. However, the story does not stop there. Modern allopathic medicine focus primarily based on systems involving pharmaceuticals and surgery. Very little emphasis is placed on the power of the mind. Even though drug trials will consider placebo and nocebo effects, still little effort is made to understand why they play a role. Furthermore, there's little explanation as to why several research...
Who am I? Ever since Sigmund Freud the concept of the ego has been an intense topic of conversation. We attempt to understand who we are in terms of not only our physical description, but also our values, beliefs, and behaviors. When all of this is considered, we just may have a reasonable concept of our “I-ness.” This can also be referred to as our ego.
In the Freud-influenced Western world a healthy mind is often synonymous with a healthy ego. This means that a stable ego is presumed to be a core requirement for the maintenance of adequate mental health. However, as normal ins-and-outs...